13. – 15. June 2022

Programme

Participants: 93, Lectures: 24, Posters: 39
List of participants
List of posters
Conference proceedings

Monday, 13. June

Registration and accomodation, 10:00-11:30

Lunch, 11:30-12:45

Warm welcome
12:45 Introduction
Daniel Svozil, University of Chemistry and Technology Prague & CZ-OPENSCREEN

Structures

Chairman: Tomáš Pluskal, Institute of Organic Chemistry And Biochemistry AS CR, Prague

13:00 Discovering the general architecture of protein families with OverProt
Adam Midlik, CEITEC, Masaryk University
abstract
13:20 Protein structure quality trends
Radka Svobodová, Masaryk University, CEITEC
abstract
13:40 A Structure Validation Concept Beyond the Static Resolution in Polymers
Vladimir Sychrovsky, UOCHB AV CR
abstract
14:00 Advanced Computational Protocol for Atomistic Understanding and Modulation of Insulin Binding to Insulin Receptor
Yevgen Yurenko, IOCB Prague
abstract

Coffee break, 14:20-15:20

Tools

Chairman: Karel Berka, Palacký University Olomouc

15:20 SeqUIa: a software platform for GUI based next-generation sequencing data analysis
Vojtech Bystry, CEITEC MU
abstract
15:40 Deep Learning the binding patterns of RNA-binding proteins using ENNGene
Eliška Chalupová, Masaryk University
abstract
16:00 Interpreting uncertainty in differential expression with DESeq2
Martin Modrák, Institute of Microbiology of the Czech Academy of Sciences
abstract
16:20 Unsupervised automated population detection and immunophenotypisation tool for analysis of multiparameter flow cytometric data
Tereza Podolská, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic
abstract
16:40 NarCoS: Integrating genomic surveillance of SARS-CoV-2 positive clinical samples in Slovak republic
Tomáš Szemes, Vedecky park Univerzity Komenskeho
abstract

Poster session, 19:00 - till complete exhaustion

Poster session is sponsored by the National Infrastructure for Chemical Biology CZ-OPENSCREEN.



    List of posters in this poster session.

19:00 Poster telegrams

The authors of 5 selected posters will introduce their work in 5 minutes long presentations. Possible questions will be answered during a subsequent poster session.
19:30 Dinner party

Tuesday, 14. June

Small molecules

Chairman: Ctibor Škuta, Institute of Molecular Genetics AS CR, Prague

09:00 Towards the interpretation of tandem mass spectra with self-supervised machine learning
Roman Bushuiev, IOCB
abstract
09:20 Machine learning estimated docking scores
Kamila Clarová, UCT Prague
abstract
09:40 Feature interrelation profiling
Ivan Čmelo, VŠCHT Praha
abstract
10:00 Circular fingerprint inversion: an algorithmic approach
Wim Dehaen, University of Chemistry and Technology, Prague
abstract

Coffee break, 10:20-11:20

Small molecules

Chairman: Ctibor Škuta, Institute of Molecular Genetics AS CR, Prague

11:20 On the Importance of Physically Correct Models for Describing Protein/Ion/Ligand Binding
Martin Lepšík, Inst. Org Chem Biochem, Czech Academy of Sciences
abstract
11:40 Multiple instance learning: a new method for 3D QSAR modelling
Maria Matveieva, VŠCHT Praha
abstract
12:00 Nature-Inspired Antivirals with Distinctive Mechanisms of Action: Focus on HIV and SARS-CoV-2
Fidele Ntie-Kang, University of Buea
abstract
12:20 Techniques for improving optimization performance of molecular generators
František Pešina, UCT
abstract

Lunch, 12:40

Leisure activities

During this time you can engage into activities unorganized by organizers. Below are some of the possibilities that the resort and the surrounding area offers:

  • For an additional fee of CZK 200 without VAT (to be paid on the spot), there will be a tasting of Moravian wines in the wine cellar of the Vigvam Resort. The owner of the resort, Mr. Petr Beníšek, is a world-renowned top sommelier, owner of several French vineyards and it will certainly be an unforgettable experience. It will also be possible to buy wines at cellar prices.
  • Bowling, table football, pool and darts will be available for the whole day.
  • There is a large mowed meadow in the grounds for e.g. frisbee. Frisbees, balls, etc. must be brought, however.
  • There are a number of interesting tourist destinations in the area (e.g. Kladruby, Kačina Castle) accessible by bike in a flat terrain.
  • From the hiking trips, yellow hiking trail to Mlejnek can be recommended.

Poster session, 19:00 - till complete exhaustion

Poster session is sponsored by the National Infrastructure for Chemical Biology CZ-OPENSCREEN.



    List of posters in this poster session.

19:00 Poster telegrams

The authors of 5 selected posters will introduce their work in 5 minutes long presentations. Possible questions will be answered during a subsequent poster session.
19:30 Yet another dinner party

Wednesday, 15. June

Sequences

Chairman: Jan Pačes, Institute of Molecular Genetics AS CR, Prague

09:00 Prediction of terpene synthase activity using self-supervised deep learning
Tomáš Pluskal, IOCB Prague
abstract
09:20 Using ChIP-nexus to decipher the architecture of transcription factor complexes
Martin Převorovský, Charles University, Faculty of Science
abstract
09:40 Transformer Language Models for Genomic Sequences
Petr Simecek, CEITEC MU
abstract

Coffee break, 10:00-11:00

Sequences

Chairman: Jan Pačes, Institute of Molecular Genetics AS CR, Prague

11:00 Modelling of Ago2 Binding using CLASH
Panagiotis Alexiou, CEITEC-MU
abstract
11:20 Prediction of sequence divergence from the quality of mapping
Viera Kovacova, IBP, University of Cologne, Germany
abstract
11:40 HiC-TE: a pipeline for HiC data analysis in the context of repeats and genome organization
Matej Lexa, Masaryk University
abstract
12:00 GC content of transposons and of their (animal) host genomes
Radka Symonova, Institute of Hydrobiology, Biology Center, Czech Academy of Sciences
abstract

Happy end
12:20 Student poster prize awards
Michal Kolář, Institute of Molecular Genetics AS CR, Prague

Lunch, 12:40