ENBIK2022 - National Bioinformatic Conference

Registration and accomodation, 10:00-11:30

Lunch, 11:30-12:45

Warm welcome

12:45	Introduction Daniel Svozil, University of Chemistry and Technology Prague & CZ-OPENSCREEN

Structures

Chairman: Tomáš Pluskal, Institute of Organic Chemistry And Biochemistry AS CR, Prague

13:00	Discovering the general architecture of protein families with OverProt Adam Midlik, CEITEC, Masaryk University abstract, presentation
13:20	Protein structure quality trends Radka Svobodová, Masaryk University, CEITEC abstract, presentation
13:40	A Structure Validation Concept Beyond the Static Resolution in Polymers Vladimir Sychrovsky, UOCHB AV CR abstract
14:00	Advanced Computational Protocol for Atomistic Understanding and Modulation of Insulin Binding to Insulin Receptor Yevgen Yurenko, IOCB Prague abstract, presentation

Coffee break, 14:20-15:20

Tools

Chairman: Karel Berka, Palacký University Olomouc

15:20	SeqUIa: a software platform for GUI based next-generation sequencing data analysis Vojtech Bystry, CEITEC MU abstract, presentation
15:40	Deep Learning the binding patterns of RNA-binding proteins using ENNGene Eliška Chalupová, Masaryk University abstract, presentation
16:00	Interpreting uncertainty in differential expression with DESeq2 Martin Modrák, Institute of Microbiology of the Czech Academy of Sciences abstract
16:20	Unsupervised automated population detection and immunophenotypisation tool for analysis of multiparameter flow cytometric data Tereza Podolská, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic abstract
16:40	NarCoS: Integrating genomic surveillance of SARS-CoV-2 positive clinical samples in Slovak republic Tomáš Szemes, Vedecky park Univerzity Komenskeho abstract, presentation

Poster session, 19:00 - till complete exhaustion

Poster session is sponsored by the National Infrastructure for Chemical Biology CZ-OPENSCREEN.

List of posters in this poster session.

19:00	Poster telegrams The authors of 5 selected posters will introduce their work in 5 minutes long presentations. Possible questions will be answered during a subsequent poster session.
19:30	Dinner party

Small molecules

Chairman: Ctibor Škuta, Institute of Molecular Genetics AS CR, Prague

09:00	Towards the interpretation of tandem mass spectra with self-supervised machine learning Roman Bushuiev, IOCB abstract
09:20	Machine learning estimated docking scores Kamila Clarová, UCT Prague abstract
09:40	Feature interrelation profiling Ivan Čmelo, VŠCHT Praha abstract, presentation
10:00	Circular fingerprint inversion: an algorithmic approach Wim Dehaen, University of Chemistry and Technology, Prague abstract, presentation

Coffee break, 10:20-11:20

Small molecules

Chairman: Ctibor Škuta, Institute of Molecular Genetics AS CR, Prague

11:20	On the Importance of Physically Correct Models for Describing Protein/Ion/Ligand Binding Martin Lepšík, Inst. Org Chem Biochem, Czech Academy of Sciences abstract, presentation
11:40	Multiple instance learning: a new method for 3D QSAR modelling Maria Matveieva, VŠCHT Praha abstract, presentation
12:00	Nature-Inspired Antivirals with Distinctive Mechanisms of Action: Focus on HIV and SARS-CoV-2 Fidele Ntie-Kang, University of Buea abstract, presentation
12:20	Techniques for improving optimization performance of molecular generators František Pešina, UCT abstract

Lunch, 12:40

Leisure activities

During this time you can engage into activities unorganized by organizers. Below are some of the possibilities that the resort and the surrounding area offers:

For an additional fee of CZK 200 without VAT (to be paid on the spot), there will be a tasting of Moravian wines in the wine cellar of the Vigvam Resort. The owner of the resort, Mr. Petr Beníšek, is a world-renowned top sommelier, owner of several French vineyards and it will certainly be an unforgettable experience. It will also be possible to buy wines at cellar prices.

Bowling, table football, pool and darts will be available for the whole day.

There is a large mowed meadow in the grounds for e.g. frisbee. Frisbees, balls, etc. must be brought, however.

There are a number of interesting tourist destinations in the area (e.g. Kladruby, Kačina Castle) accessible by bike in a flat terrain.

From the hiking trips, yellow hiking trail to Mlejnek can be recommended.

Poster session, 19:00 - till complete exhaustion

Poster session is sponsored by the National Infrastructure for Chemical Biology CZ-OPENSCREEN.

List of posters in this poster session.

19:00	Poster telegrams The authors of 5 selected posters will introduce their work in 5 minutes long presentations. Possible questions will be answered during a subsequent poster session.
19:30	Yet another dinner party

Sequences

Chairman: Jan Pačes, Institute of Molecular Genetics AS CR, Prague

09:00	Prediction of terpene synthase activity using self-supervised deep learning Tomáš Pluskal, IOCB Prague abstract
09:20	Using ChIP-nexus to decipher the architecture of transcription factor complexes Martin Převorovský, Charles University, Faculty of Science abstract, presentation
09:40	Transformer Language Models for Genomic Sequences Petr Simecek, CEITEC MU abstract

Coffee break, 10:00-11:00

Sequences

Chairman: Jan Pačes, Institute of Molecular Genetics AS CR, Prague

11:00	Modelling of Ago2 Binding using CLASH Panagiotis Alexiou, CEITEC-MU abstract, presentation
11:20	Prediction of sequence divergence from the quality of mapping Viera Kovacova, IBP, University of Cologne, Germany abstract, presentation
11:40	HiC-TE: a pipeline for HiC data analysis in the context of repeats and genome organization Matej Lexa, Masaryk University abstract, presentation
12:00	GC content of transposons and of their (animal) host genomes Radka Symonova, Institute of Hydrobiology, Biology Center, Czech Academy of Sciences abstract, presentation

Happy end

12:20	Student poster prize awards Michal Kolář, Institute of Molecular Genetics AS CR, Prague

Lunch, 12:40

Programme

Monday, 13. June

Tuesday, 14. June

Wednesday, 15. June