09. – 11. June 2025

Programme

Participants: 67, Lectures: 24, Posters: 25

Monday, 9. June

Registration and accomodation, 10:00-11:30
Lunch, 11:30-12:45
Warm welcome
12:45 Introduction
Daniel Svozil, University of Chemistry and Technology Prague & CZ-OPENSCREEN
Sequences

Chairman: David Hoksza, Faculty of Mathematics and Physics, Charles University Prague

13:00
Efficient Analysis of Genome Annotation Colocalization
Broňa Brejová, Univerzita Komenského v Bratislave, Bratislava
13:20
Elastic-Degenerate Strings in Bioinformatics: Motivation and Open Problems
Dominika Bohuslavová, Czech Technical University in Prague, Faculty of Information Technology, Prague 6
13:40
Plasmid Identification Through Graph Neural Networks
Tomáš Vinař, Univerzita Komenského v Bratislave, Bratislava
14:00
Cryptic binding site detection with protein language models
Vít Škrhák, Charles University, MFF, Praha 1
Coffee break, 14:20-15:20
Small molecules

Chairman: Karel Berka, Palacky University Olomouc

15:20
Handling Compound Promiscuity in CZ-OPENSCREEN
Adam Hanzlík, Ústav molekulární genetiky AV ČR, v.v.i., Praha 4 – Krč
15:40
QSPRpred, Spock and DrugEx: Developing an Open Source Ecosystem for Cheminformatics
Martin Šícho, VŠCHT Praha, Prague
16:00
Fragment-based de novo design and searching for hit molecules in ultra-large chemical libraries
Pavel Polishchuk, Palacky University, Faculty of Medicine and Dentistry, Olomouc
16:00
Ligand hallucinations in cofolding methods
Wim Dehaen, UCT Prague, Praha 6
16:20
Quantum-Mechanics Based Multiscale Modeling and Rational Design of Insulin Analogs with Improved Binding Affinities
Yevgen Yurenko, Institute of Organic Chemistry and Biochemistry, Prague, Prague
Poster session, 19:00 - till complete exhaustion

Poster session is sponsored by the National Infrastructure for Chemical Biology CZ-OPENSCREEN.



List of posters in this poster session.

19:00 Poster telegrams
The authors of 5 selected posters will introduce their work in 5 minutes long presentations. Possible questions will be answered during a subsequent poster session.
19:30 Dinner party

Tuesday, 10. June

Sequences

Charmain: Karel Sedlář, Brno University of Technology

09:00
Crazy avian genome, stuttering genes, and why we love nanopore
Tomas Hron, Institute of Molecular Genetics, AV CR, v.v.i., Prague
09:20
Structural variation in closely related songbird species
Zuzana Halenková, Faculty of Science, Charles University, Praha 2
09:40
Plasmid-Mediated Antibiotic Resistance Dynamics in Broiler Chickens Revealed by Long-Read Sequencing
Darina Čejková, Brno University of Technology, Brno
10:00
Analyzing Retrotransposons in RNA Data: Can I Hand It Over to AI or Do I Still Have to Work?
Pavel Ostašov, Faculty of Medicine in Pilsen, Pilsen
Coffee break, 10:20-11:20
Tools

Chairman: Martin Šícho, University of Chemical Technology Prague

11:20
5 years of Alphafoldology
Karel Berka, Palacky University Olomouc, Olomouc
11:40
MARTS-DB: The Mechanisms And Reactions of Terpene Synthases DataBase
Martin Engst, Ústav organické chemie a biochemie AV ČR, v. v. i., Praha 6
12:00
mutation_scatter_plot: Tackling codon usage analysis from a different angle
Martin Mokrejš, Charles University, First Faculty of Medicine, Prague
12:20
Predicting Gene Regulatory Networks with Augusta
Karel Sedlář, Vysoké učení technické v Brně, Brno
12:40
Negative Reference Extraction for Machine-Assisted Flow Cytometry Immunophenotyping
Karel Fišer, Univerzita Karlova, 2. lékařská fakulta, Praha
Lunch, 13:00
Leisure activities

During this time you can engage into activities unorganized by organizers. Below are some of the possibilities that the resort and the surrounding area offers:

  • The hotel has a wide range of sports facilities, such as an indoor swimming pool, gym, fitness and more, see here.
  • Wellness will be available at a discounted price.
  • Adventure golf is located in Karlov pod Pradědem.
  • The Jeseníky Protected Landscape Area offers a number of interesting hiking trails directly from the hotel.

Poster session, 19:00 - till complete exhaustion

Poster session is sponsored by the National Infrastructure for Chemical Biology CZ-OPENSCREEN.



List of posters in this poster session.

19:00 Poster telegrams
The authors of 5 selected posters will introduce their work in 5 minutes long presentations. Possible questions will be answered during a subsequent poster session.
19:30 Yet another dinner party

Wednesday, 11. June

Sequences

Chairman: Martin Mokrejš, First Faculty of Medicine, Charles University Prague

09:00
Modeling changes in cell populations between groups of samples of scRNA-seq data
Martin Modrák, Second Faculty of Medicine, Charles University in Prague, Praha 5
09:20
Ancient DNA Computational Genomics: Tracing Human Origins and Mobility in Prehistoric Europe
Edvard Ehler, Ústav molekulární genetiky AV ČR, v. v. i., Praha 4
09:40
Identifying intercellular patterns in Vestibular schwannoma
Lucie Pfeiferová, Ústav molekulární genetiky AV ČR, v. v. i., Praha 4
Coffee break, 10:00-11:00
Sequences

Chairman: Tomáš Vinař, Comenius University Bratislava

11:00
Bioinformatics approaches to studying the relationships between structure, function and evolution of amylolytic enzymes – the case of the alpha-amylase family GH57
Štefan Janeček, Institute of Molecular Biology, Slovak Academy of Sciences, Bratislava
11:20
Streamlined workflow for bacterial methylation analysis using nanopore data
Markéta Jakubíčková, Brno University of Technology, Department of Biomedical Engineering, Brno
11:40
Rapid genetic change in the passerine germline restricted chromosome
Stephen Schlebusch, Charles University, Prague 1
Happy end
12:00 Student poster prize awards
Edvard Ehler, Institute of Molecular Genetics AS CR, Prague
Lunch, 12:30